Impact of Co-Culture on the Metabolism of Marine Microorganisms - Université de Perpignan Via Domitia Access content directly
Journal Articles Marine drugs Year : 2022

Impact of Co-Culture on the Metabolism of Marine Microorganisms

Abstract

Natural products from plants have been listed for hundreds of years as a source of biologically active molecules. In recent years, the marine environment has demonstrated its ability to provide new structural entities. More than 70% of our planet’s surface is covered by oceans, and with the technical advances in diving and remotely operated vehicles, it is becoming easier to collect samples. Although the risk of rediscovery is significant, the discovery of silent gene clusters and innovative analytical techniques has renewed interest in natural product research. Different strategies have been proposed to activate these silent genes, including co-culture, or mixed fermentation, a cultivation-based approach. This review highlights the potential of co-culture of marine microorganisms to induce the production of new metabolites as well as to increase the yields of respective target metabolites with pharmacological potential, and moreover to indirectly improve the biological activity of a crude extract.
Fichier principal
Vignette du fichier
marinedrugs-20-00153.pdf (2.15 Mo) Télécharger le fichier
Origin Publication funded by an institution

Dates and versions

hal-03841284 , version 1 (07-11-2022)

Licence

Identifiers

Cite

Flore Caudal, Nathalie Tapissier-Bontemps, Ru Angelie Edrada-Ebel. Impact of Co-Culture on the Metabolism of Marine Microorganisms. Marine drugs, 2022, 20 (2), pp.153. ⟨10.3390/md20020153⟩. ⟨hal-03841284⟩
76 View
73 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More